Phase II - Search and Destroy/Supplements

      Phase II is the Special Forces Part of the Battle to eliminate your Peyronie's Disease enemy.  
 Before taking any regimen of enzyme treatment, make sure and consult with your doctor.  It is especially important if you are taking blood thinners or cholesterol reducing meds, to make sure that the enzymes in this plan will not contradict, enhance, or interfere with other prescribed medications you are taking.  

Serrapeptase:


       I'll start off with what has been described as the "Miracle Enzyme,"  by Hans Neiper.  He was a legendary medical doctor that was known for his use of proteolytic enzymes.  Serrapeptase has been used widely in clinical practice in Japan and Europe, for over 30 years.  Serrapeptase is an enzyme that was isolated from non-pathogenic bacteria found in the digestive tract of the Japanese silkworm.  This powerful enzyme is what allows the moth to dissolve it's cocoon.  This miracle enzyme digests dead tissue, such as blood clots, cysts, arterial plaque and internal scar tissue. 

Nattokinase:

       Nattokinase helps the body maintain healthy circulation.  It has been a traditional Japanese folk remedy that has been valued as a food for over 1000 years.  Natto is a fermented soy food that contains important enzymes.  Nattokinase is unmatched by any other food derived enzyme for its' circulation enhancing effects.

Natto on Rice - an acquired taste
        Nattokinase promotes all around health for the heart, brain and muscles by helping the body keep blood flowing in a healthy way.  It also increases oxygen supply to all organs, by increasing circulation.  Nattokinase digest dead proteins in the obdy.  This is its' primary function in battling Peyronie's disease.  Increased circulation is an additional benefit in aiding erection quality and boosting overall cardiovascular health.
       Dr. Hiroyuki Sumi researched with Natto, searching for a natural agent that would dissolve thrombus (fibrin) that is associated with cardiac and cerebral infarction.  He found that Natto was a potent enzyme for this purpose.  Dr. Sumi named the newly discovered enzyme "Nattokinase," which means enzyme in Natto.

Acetyl-L-Carnitine:


       Acetyl-L-Carnitine is an amino acid the body uses to turn fat into energy.  This amino acid is sometimes referred to as natural Prozac.  The emotional boost it gives is definitely noticeable.  It can be taken with or without food and is very safe and well tolerated.  Acetyl-L-Carnitine and the drug Tamoxifen were compared in a 3 month double blind study on 38 men with Peyronie's disease in Turin, Italy.  Acetyl-L-Carnitine (at a dose of 1gm. daily) reduced penile curvature, while Tamoxifen did not.  In a ddition the supplement reduced pain and slowed disease progression.  The other benefit of Acetyl-L-Carnitine over Tamoxifen was a lack of side effects.

Omega-3 Fish Oil:

Many Urologists that treat Peyronie's disease will prescribe vitamin E, but large doses have been known to over thin the blood, which can be dangerous for cardiovascular health.  Omega-3 Fish oil provides all of the benefits of vitamin E, with the added benefit of supporting cardiovascular health and raise the good cholesterol levels.
       The benefits of vitamin E in the treatment of Peyronie's disease are inconclusive, especially considering how long vitamin E has been prescribed for treatment.  double blind study results have been disappointing.  Vitamin E provides more benefit when used in topical applications.  (See treatment phase III for more information)

Treatment Doses:

Serrapeptase and Nattokinase should be taken without food between meals, or one hour before eating.  This is important, because the enzymes need to activate in the lower intestine, so they can be absorbed into the blood stream, where they will perform their primary function.  If they are taken with food, they absorb the protein in the food and are passed through your body as waste.  The same instructions apply to Blockbuster All Clear. 

Serrapeptase, Nattokinase and Acetyl-L-Carnitine should be taken together, twice daily or take Blockbuster All Clear and Acetyl-L-Carnitine twice daily.  I took them upon waking up each morning and before going to bed in the evening, so that my stomach would be as empty as possible.  Then in the evening take an additional Serrapeptase, Nattokinase or Blockbuster All Clear, do not take Acetyl-L-Carnitine in the evening as it will make it difficult to fall asleep.

Omega-3 Fish Oil should be taken with meals, but it should not be taken with Serrapeptase, Nattokinase or Blockbuster All Clear, as it is a protein food product, and it will reduce the enzyme's effectiveness. You can take 2 or more capsules every day.

Note:  Acetyl-L-Carnitine can cause some people to have symptoms of overstimulation and insomnia with large doses.  Acetyl-L-Carnitine can be taken with or without food, so if you have these symptoms, you might consider taking the second dose earlier in the day.

Next: Serrapeptase in Ph. II

44 comments:

  1. HI. I've had Peyronie's for over 3 years now and so far i've yet to find anything to stop it progressing, and your ideas sound very interesting. My question to you is: do you recommend taking the omega-3 after the course of serra, natt, and acet is finished? Or would you take a capsule at lunch during the meal? Thanks.

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  2. I still take an Omega-3 everyday, I also take Natto and Serrapeptase for Cardio health. It has lowered my Cholesterol. My doctor put me on Statins several years back, and I no longer need to take them.

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  3. Hello. My Peyronie's started about 2 months ago. What were the dosages of the serrapeptase, nattokinase, and acetyl-l-carnitine, that you took at one time, of your twice daily regimen? Thank you for your answer and this website.

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  4. John,

    Can you give me your recommended doseage on Natto, Serra & Acetyl - L for PD?

    Thanks,

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  5. Hi John,

    Thanks so much for your website. It has provided hope for me that things possibly could get better. I have one question. Did you find there were still signs of your Peyronie's there after the treatment, such as indentation, hardness, still a slight curve etc? Or have all the signs of Peyronie's disappeared completely?

    I'm currently still in the middle stages of the disease it seems (even though I've had it for 6 years!). I'm currently using most of the treatments you advise on your website, plus a couple of others, and also using the male edge traction device. I find it does help with straightening slightly but if I leave it for a few days the bend again starts to worsen. This is probably because it has not fully stabalised as yet. I also feel that even though I may be helping out with the straightening, I am losing girth instead on that side. I'm also forming an indentation at the area of bend which I think will always be there, even if I avoid too much bending in that area. I wondered if this was the case for you, or do you feel you are completely cured?

    Thanks in advance for your help.

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  6. Sorry about the delay in replying to your questions. I've been working in California for two months and away from the website.

    I started taking 40,000 serratio units of Serrapeptase and 2,000 FU's of Nattokinase twice daily without food. I took them upon waking up in the morning and in the evening before going to bed. Try and time taking them when your stomach is the most empty, so you do not waste the benefits of these enzymes. If you take them with food, they will dissolve in your stomach and bind to the proteins in the food and pass through. The enteric coating helps the caps to pass through your stomach into the intestine, where they will give you the best results and benefits.

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  7. Hey John,

    I just turned 21 and I have been diagnosed with Peyronie's. My case is rare in that I don't have a bend at all, but a severe hourglass deformity at the base of my penis. I just ordered all of the nutrients and etc. that you suggested, except for the stretch device since my doctor said it wouldn't help me in my case.

    I'd say I've had this for about a year, and I'm not sure if it has fully stabilized or not.

    You said that your condition stabilized but was then cured when you developed this plan...

    Do you think that I have a good chance of restoring my penis back to its normal girth? If so, how long will this take? I will strictly follow your plan to the letter.

    Thanks!

    -A concerned young man

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    Replies
    1. Thanks for your comment,
      I'm sure sorry that you have developed Peyronie's at such a young age. It is really uncommon but not unheard of for your men to develop a plaque.

      I think you have a good chance of restoring your penis. One of the things that I made sure to do was use a hot wash cloth as a hot compress before applying the topical gel. This raises the temperature of the tissue and studies have shown that heat treatment (hyperthermia) is effective in softening and unwinding the collagen molecule. Softening the plaque before applying the gel will help the DMSO/SSKI/Vit.E to be its' most effective in the job of scar reduction.

      I do not know how long it will take, every man is different. You should have a better chance at your young age, because your circulation should be better, than older men. With Peyronie's disease there is no 100% guarantee of successful treatment due to different causes and different body types and physical conditions. Keep being pro-active and try and keep a positive mental attitude. A positive outlook is essential in healing.

      Best Wishes for a Quick and Complete Recovery,
      John Parks

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  8. Neprinol; is that specifically for congenital curvatures?

    I have just begun to take Serrapaptase and Nattokinase + DMSO and SKSI. Is it important to take Neprinol as well?

    I probably have both PD and congenital curvature.

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    Replies
    1. Neprinol is a combination supplement that includes Serrapeptase and Nattokinase in one capsule. If you take the enzymes separately and also take Neprinol, then you are doubling up on your intake. If you have already purchased Neprinol their suggested dosage information is at this site:
      http://www.neprinol.com/neprinol-dosage/#question03
      There is nothing that you can take orally that will affect congenital curvature. This is an issue where your penis has a natural curve, that is not caused by injury or any kind of buildup. Many men have some amount of congenital curvature.
      If you have had a curved erect penis since childhood, that is a pretty good indication that it is congenital. Traction devices have been found to help correct congenital curvature, but taking any supplements, enzymes, etc. will not affect a natural curve.

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  9. I have now used Serrapaptase and Nattokinase for around 1 month. I have also used the DMSO and Organic Iodine Oil (topical) + taken Nascent Iodine along with water.

    As I think I have a scar just beneath my left glans ( I think that is the case rather than an extension of the right side of the penis), and the difference is easy to see when it is rock hard. So I don`t think there has been an improvement with the scar.
    How long time can it take to make the scar to dissolve??
    Any other suggestions? I have drinken some alcohol, but don`t think it can play that big part. My sugar intake is much less than before.

    One tip maybe others can do if they think their left or right curve is too big; When holding the penis, try to twist the shaft, the top of it to be horizontal. This is not cheating the reality about the penis, it is the truth about how it really is (at least for mine). For me, this little thing changes the look of the curve to decrease very much, so now my curve is maybe just 10 degrees (a little bit more when rock hard) :))
    This technique can also be understood using it on a banana.

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    Replies
    1. I began to notice a change in curvature around 9 weeks into my treatment program. Everybody is different and will respond differently to treatment. A lot depends on how long you have had the plaque. Over time the plaque becomes more stable and harder, which makes it more difficult to treat as effectively. The best time to treat Peyronie's is in the initial acute stage, when the plaque has not yet become hard and stable. I personally would still try alternative treatment on a stable plaque in lieu of surgery.

      A high percentage of men with Peyronie's have been linked to Diabetes and pre-diabetic conditions. Alcohol and sugar intake may have an effect on Peyronie's, but there is no proven casual link at this time. It is a good idea for a man with Peyronie's to be tested for insulin resistance and to control their alcohol and sugar intake.

      For curvature correction and regaining lost length, I believe traction devices are most effective, as they can provide pressure for long periods of time against the curvature and help lengthen a penis that has retracted. I always tried to position my penis in my underwear so that it would curve the opposite direction, while it was not in traction. It will tend to go back to the curved position, so it takes diligence and frequent re-adjusting.

      Thanks for the tip and question.

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  10. Hi John,
    Anyone else report increased focus an hour after taking the ALC? Not bad, I like it.


    Also, I notice a weird chemical taste 30 minutes or so after applying the DMSO Vit-E. My young daughter has commented on 'yucky breath'. Since I make the DMSO application around the same time as taking the pills, I can't pinpoint the culprit. I just brush/gargle a few more times a day & make cetain not to get too close to others when talking. Causes? Comments?

    Thanks again for your site!

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  11. Thank you for your comment, Sorry about the delay in posting it. I lost quite a few emails in April while moving. The computer was bumped and became unplugged while it was running. I noticed later that the emails from that time period had been deleted somehow. I found your comment while going through the blog comment archive.

    I noticed an increase in focus after taking Acetyl L Carnitine, and also if I took it too late, it was hard to fall asleep.

    My wife didn't like the garlic smell from the DMSO. Some men complain about the odor and others seem unaffected by it. Acetyl L Carnitine can leave you with a sour/acid kind of smell on your breath. I noticed a distinct Acetic Acid smell sometimes. I recognize the smell from my old days developing film in the dark room and the stop bath was water and Acetic Acid. Thank goodness for digital camera's.

    Anyway the smell your daughter is commenting on, more than likely is from the DMSO, but it also could be a combination of the two.

    I am glad that you are benefiting from the information here at this site.

    Thank you - John Parks

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  12. The "natural prozac" comment has effectively turned me off of trying Acetyl-L-Carnitine. Prozac is not a good thing; no psychotropic is. I want to reduce/soften the scar tissue so I don't experience the pain ... I don't want anything that is going to mess with my head.

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    1. Acetyl L Carnitine is not a psychotropic, it is an amino acid (a building block for proteins) that is naturally produced in the body. It helps the body produce energy.
      Excerpt from WebMD.com
      Acetyl-L-carnitine is used for a variety of mental disorders including Alzheimer's disease, age-related memory loss, late-life depression, thinking problems related to alcoholism, and thinking problems related to Lyme disease. It is also used for Down syndrome, poor circulation in the brain, cataracts, nerve pain due to diabetes, nerve pain due to drugs used in the treatment of AIDS, and facial paralysis.

      Some men use acetyl-L-carnitine for infertility, symptoms of “male menopause” (low testosterone levels due to aging), and a disease of the penis called Peyronie’s disease.

      Many men notice an increase in energy levels and an increased feeling of well being. It is a natural by product of taking this supplement.

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    2. Thank you for your comment, I just wanted to add that Prozac is a Seratonin re-uptake inhibitor. It actually can change the chemical functions in the brain and how Seratonin is naturally released. It effectively can rewire some of the functions of the brain.

      The comment I made about Acetyl L Carnitine working as a "natural prozac" was in relation to that "boost" that many men feel after taking it. It is an energy boost as the amino acids kick in to burn fat and build protein. If is does mess with your head, it is in a good way, since L-Carnitine deficiencies can appear as mental confusion or cloudiness.

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  13. The "natural prozac" comment has effectively turned me off of trying Acetyl-L-Carnitine. Prozac is not a good thing; no psychotropic is. I want to reduce/soften the scar tissue so I don't experience the pain ... I don't want anything that is going to mess with my head.

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  14. Hey John, what would you class as a mild or acute case of Peyronie's (angles wise)? I think that my case is fairly mild. Will Acetyl-L-Carnitine get rid of the plaque and reduce penis curvature over time?

    Thanks

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  15. I would consider an acute case or chronic case of Peyronie's would be any curvature of 30 degrees or more. Any bend or curvature that prevents sexual intercourse or makes it uncomfortable would be acute. Most of the time clinical trials are looking for men with a 30 degree angle or more. So that is a pretty much, in my opinion a standard between mild/moderate to acute/chronic Peyronie's.

    Acetyl-L-Carnitine for treating Peyronie's, the recommended dose is 1000 mg. twice daily. I would also supplement it with Serrapeptase/Nattokinase to assist in carrying away the fibrin and reduce inflammation. A superior Serrapepatse/Nattokinase blend is made by Robert Redfern it is more expensive than Dr.'s Best and less expensive than Neprinol. Robert's blend is called Blockbuster All Clear. I used Dr.'s Best but did not know about Blockbuster All Clear at the time.

    I hope this is helpful for you, Thank you for your questions.

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    1. Thanks for the quick reply and the info + advice. I had already gotten the Dr.'s best before reading this and having been taking 500g 2x p/ day and also omega-3. I'll see how it goes over the next 2-3 months and then re-evaluate based on the results. How much affect do you think these will have on my Peyronie's disease? Thank you so much for creating this website!!

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    2. Dr's. Best is a high quality brand and should work well for you. I just found out about Robert Redfern's blend recently and believe it is an improvement over Dr.'s Best. The treatment that was used in the clinical studies using Acetyl-L-Carnitine VS. Tamoxifen used double the dose your are presently taking. They administered 1000 mg. (2 capsules) twice a day. Don't take ACL too late in the evening or it will tend to keep you awake.

      Omega 3 tests were inconclusive, but one of the problems with the double blind placebo test, was that they were taking very small quantities of Omega 3 daily. In my opinion, not enough to make a difference. The dosage of Omega 3's should have been higher.

      Thank you for your questions and kind words, Best wishes for a quick recovery.
      John Parks

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  16. What dosage of Acetyl-L-Carnitine should I take per day? I have Dr.'s Best 500mg. How many of those should I take per day?

    Thanks

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  17. The recommended dosage for Acetyl-L-Carnitine should be take two in the morning and two in the afternoon. I was not taking that much, but since that time I have read studies that recommend 1000mg. twice daily. Do not take ALC, in the evening if you want to fall asleep. It does give you somewhat of a boost and will make it hard to go to sleep.
    Thank you for your question - John

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  18. Hi John,

    Thanks so much for creating this blog and sharing your experience... I just found out I have peronies a couple months ago not knowing what was going on... About 10 months ago is when I first notice the scar tissue lump... I have been taking fish oil, vitamin E and CoQ10 the past couple months which has helped, mainly when it comes to erection pain... I have just ordered the acetyl-l-carnitine, nattokinase and serrapepatse and am hoping to see more results, since I'm only around a 10-20% bend at this time... I guess my question is, how long does one need to keep taking these supplements and could things get worse if one stops?
    Please let me know,
    Thank you

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    Replies
    1. The recommended dose for Acetyl-L-Carnitine is two capsules twice daily, which comes out to 2 grams or 2,000 mg. a day. Take ACL early in the day and in the afternoon. If you take it too late in the day, you will probably have a hard time falling asleep. Serrapeptase and Nattokinase should be taken on an empty stomach, as they would combine with food in the stomach and bind with the proteins there. I also would recommend taking two of each three times a day. Morning before eating, mid afternoon and evening. You should follow this protocol for 3 months, then you can lower the dosage to one capsule each with the same frequency.

      I still take Serrapeptase and Nattokinase daily, for cardiovascular health. Robert Redfern's formula Blockbuster All Clear is the best Serra-Natto combination in my opinion, it is a little more expensive, but it is effective. I hope this information is helpful and thank you for your kind words and questions.

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  19. Hi, I was at around 60% with my PD and my doctor recommended surgery. I did have surgery to remove the plaque in June. I'm sad to say at this point I believe the scar is even harder and the curve the same as it was. My doctor now said I shouldn't have another surgery because the same thing would happen. I'm still healing since June so do you have a recommendation on anything else like Ziaflex? I'm on your program right now since July but so far have no results. Also, the Acetyl-L-Carnitine says to take it with meals on the bottle. I do notice a burning in my stomach after taking it without meals but not when I eat. What do you think is the right thing to do?

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    Replies
    1. I am sure sorry to hear about your complications with surgery. You should talk with your doctor about my program. Print out the book and let him check it out. Some surgeons use permanent stitches and traction should not be attempted if the stitches are permanent.

      I don't want to be the bearer of bad news, but Xiaflex is best used for men in the earlier stages, before the plaque has calcified. It still is not available until FDA approval. The clinical trial acceptance parameters were for men with non-calcified plaques.

      I think hot compresses could be effective, so that you could increase the blood flow in the area where the plaque was removed. Your surgeon probably used a graft that takes some time for the blood to flow into, and re-build in to more natural tissue. Hot compresses may help soften this area and aid, by increasing circulation to the scar area..

      With the supplements you should take Serrapeptase and Nattokinase without food and Acetyl-L-Carnitine and Fish Oil with Meals. I wish I could be more helpful, but I don't know what type of surgical procedure was done and if the program could cause more damage than good after having surgery. I would definitely consult with your doctor about the safety of using traction.

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  20. Hi John, I'm the previous comment about the 60 degree PD and surgery. This week I was checked out and sad to say that I'm now at a 70 degree angle with my curvature. It has only been a month going from 60% to 70% so I'm becoming more afraid at this point. I explained a lot of your information to my doctor but he doesn't believe that the DMSO with E can do anything with the hardened plaque and went through a bunch of reasons scientifically of how this isn't possible. He does think the DMSO can penetrate but that's it. So, now my choice is thinning because unfortunately this program hasn't worked yet for me although I'm still trying without the traction. I've purchased the kit a few months ago but not using any traction device My doctor is highly recommending Verapamil because he claims success with more than 60% of his clients. He also believes Ziaflex wouldn't be a strong candidate for the reasons you listed above and it may not be out until next year. I did read that you thought Verapamil wasn't a great choice but what do you think of it as my last option since I can't have another surgery. I'm also experiencing pain now most of the time even when I'm not erect. Thanks again for shedding some light on this for me.

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    1. Verapamil does not have a great track record. Many injection studies using Verapamil and placebo injections of saline have shown that Verapamil does reduce some curvature, but also the saline injections were in the same range of improvement. I think the fact that a needle has been inserted into the plaque may have something to do with the noticed improvement, as the needle would disturb and possibly break up the plaque somewhat.

      Verapamil is a calcium channel blocker drug. It is thought that by blocking calcium, which is part of the plaque it will slow the production of collagen, which is what comprises the non-elastic tissue of the plaque and causes deformity or curvature. Verapamil is thought to reorganize the collagen and thus reduce curvature. It is similar to Xiaflex, in respect to being much more effective in the early inflammatory stages of Peyronie's. Verapamil, much like Potassium Iodide has been found to be effective in treating Keloid scars and burn scars. That is the reason for combining DMSO and Potassium Iodide (SSKI). The DMSO will carry the SSKI to the plaque, as SSKI/Iodine has a low molecular weight and is easily carried by DMSO through the skin.

      Your particular case is different though, since you have had surgery, which makes it much more complicated to treat. If your doctor believes that Verapamil injections will work for you, I would be willing to give it a go, if I were in your shoes. I would also try traction if there are not any permanent sutures and your doctor says it is safe to proceed in that direction. It also depends on how much pain you are in. It would be helpful to know a more details about your surgery. Feel free to email me at: midlifehealthanswers@gmail.com

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  21. This comment has been removed by a blog administrator.

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  22. Hello John,

    I have had a relatively mild case of peyronies for about 6 months now. It has had a huge impact on me, especially psychologically due to embarrassment. I am very young but optimistic about reversing this disease. I was wanting to know how big of a role diet and exercise plays in the treatment of Peyronies? I am starting to eat healthier (eating a lot of fruits and vegetables) and I do enjoy lifting weights. I have heard that increasing testosterone levels may help in the treatment of peyronies but i'm not sure if thats valid. And also, im a little hesitant when it comes to applying the DMSO. Is there any potentially severe side effects with the DMSO besides the garlic odor? And when you say "garlic smell", does this last throughout the whole day? Thank you for all your help!

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  23. DMSO has been used safely for many years. The garlic smell is a byproduct of using it and, yes it does last throughout the day. It isn't really strong, but those who get very close to you will probably notice it. Being positive and optimistic is critical to success in overcoming Peyronie's. A healthy diet and lifestyle is also very helpful to the healing process. My personal diet changes include eating healthy fats, such as grass fed beef, free range chicken and wild caught fish. I avoid most dairy, but not all, and have cut way back on my gluten intake. Eating a lot of fresh fruits and veggies is essential. Many people do not think there are enough nutrients in produce today, due to mineral depletion in the soil. I'm not big on supplements personally, because taking too much glucosamine may have been a big contributor to Peyronie's in my case. I think the jury is out on taking a bunch of vitamins and supplements. I do know that there is not enough iodine in our diets and I do drink 4 drops of nascent iodine daily in a glass of water. These are not recommendations, just a loose guide line for healthy diet changes, that most men would benefit by adopting.

    Thank you for your comment and observations. I wish you success in your treatment and overcoming this affliction. John Parks

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  24. John,

    Would you recommend a penis pump over the traction devices for pd treatment?

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    Replies
    1. I definitely believe the effectiveness and safety of a traction device outweigh the benefits and safety concerns of using a penis pump. The traction device can be adjusted to pull directionally on the penis, especially the new "Peyronie's Device" that you can see listed in the column to the right of this article. Also traction devices are much safer to use than a penis pump, as there is little chance of incurring a injury in their use, unless the user puts too much tension on the spring arms that provide pressure and tension.

      The disadvantage of penis pumps is they are not adjustable and there are many cases of injury using vacuum devices. Too much vacuum can increase the injury and worsen curvature. Thank you for your question, I hope this helps to clear up any confusion you may have on this subject.

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    2. Hello,

      I was wondering if you had any other information regarding glucosamine? I was taking it in moderate dosages, when I developed PD. I have severe arthritis and wanted to be sure glucosamine is the culprit before I stop taking it. Thank you for all your contributions regarding this "disease".

      Delete
    3. Glucosamine is one possible culprit in Peyronie's. Micro injuries, along with genetic pre-disposition is in my opinion the main cause of PD. I think mine was a combination of all three. First of all I was taking a lot of glucosamine in the form of: Knox NutraJoint Glucosamine With Gelatin. I was drinking it everyday and it really made my back and joint problems a thing of the past.

      It turned out that drinking it everday was the equivalent of taking 7,000 mg or 7 grams a day. This is an excessive amount and my doctor agreed with me, that it probably was a major contributor to my PD and the TIA stroke that I had near the same time. A MRI and Carotid Artery ultrasound did not find any evidence of heart disease or arterial plaque build up, so the logical conclusion was glocosamine was more than likely the culprit. Check on the form of glucosamine you are taking and the amount, then I would talk with your physician about this, before you stop taking it. I do have back pain now that I have discontinued its' use. I just need the discipline to start a core strengthening program and cut out the sugars in my diet. I believe this would help immensely with the back problems. I am not willing to resume any use of glucosamine, as I do not want to ever have a relapse of PD. Thank you for your question. I hope this information is helpful.

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  25. Hello, John!
    Thank's for your positive contribution to this problem!

    I have a question about Blockbuster All Clear:
    This product consist not only of Serrapeptase and Nattokinase, but also from other components and enzyms, there are:
    Protease, Lipase, Amylase, Cellulase, Lactase, Acerola, Extract Amla, Extract Olive, Citrus Blend, Trace Minerals (Coral Calcium), Bacillus Coagulans, Protease S, Grapeseed, Extract Pycnogenol, Policosanol.

    We should use Blockbuster All Clear (because of Serrapeptase and Nattokinase) twice a day as you recommend. But with these (Ser. adn Nat.) we also automatically use another components that i have written.

    So, do we need these another components? And don't hurt they us?

    Thank you!

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  26. Thanks for your kind comments and question. Blockbuster All Clear is a formulation developed by Robert Redfern. This formula was designed for treating connective tissue disorders, and inflammation. Robert recommends Blockbuster AllClear specifically for treating Peyronie's Disease.

    Blockbuster AllClear is a powerful blend of proteolitic enzymes and they felt that there was still room for improvement so they made the following changes:

    Protease: is responsible for digesting protein in your food, to keep undigested protein from passing into your circulatory system.
    Lipase: is an essential enzyme that breaks down fats into smaller components
    Amylase: is a digestive enzyme that breaks starch down into smaller carbohydrate molecules. Amylase is believed to provide resistance for swelling and redness.
    Cellulase: helps break down and digest cellulose into energy-sustaining blood sugar.
    Lactase assists in the digestion of dairy products
    Acerola extract acts as a free radical scavenger for the skin.
    Olive Citrus Blend is a powerful antioxidant, that according to studies is effective in lowering bad cholesterol levels.
    Coral minerals are highly absorb able and help reduce chronic acidosis. Chronic Acidosis leads to bone thinning and osteoporosis, which can lead to excess calcium levels in the blood stream.
    Bacillus Coagulans; is a probiotic that holds promise in boosting immunity.

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  27. "Robert recommends Blockbuster AllClear specifically for treating Peyronie's Disease." - Oh, in this way I have no question. Because I thought that this blend is not specific and is restorative nature (that other components are embedded without considering the peculiarities of the disease and can hurt if we will use it based on Serrapeptase and Nattokinase dose).

    And how do you think, should we use Calcium, drink milk, grainy curd, cheese and so on? Could this lead to precipitation of calcium in the damaged and problem tissues?

    Sorry for my English.

    Thank you, John!

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    1. All of us need calcium to keep our bones healthy and maintain muscle mass. I have not read anything about dairy calcium and a causal link to calcification in Peyronie's plaques. We also ingest calcium in many dark green vegetables and many of us to a certain degree in our water. Calcification of the plaque, could be similar to other calcium deficiency diseases like kidney stones, gallstones, and osteoporosis. In these conditions, calcium migrates away from the bones and into places it is not needed or wanted. High mineral calcium content in water, and in supplements, is the cause of stones and calcification in some people, since it is not metabolized as well as natural forms of calcium found in food.

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  28. John

    Do you think a hot tub would help? Mine is set at 104 degrees

    thx

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    1. I wish I had a hot tub, when this was going on. I think it would be helpful, just don't stay in too long. If you want a longer duration, stay in the tub from the waist down. A hot tub will not completely replace the need for hot compresses, but it is therapeutic and should aid in healing. Years ago, I had an accident where I severed my thumb with a skilsaw. The orthopedic surgeon re-attached it in a 4 hour operation. During physical therapy they had me put my hand in a hot tub, and it really did help. So yes, I think it is a great idea.

      Thank you for your question, it is something I never really thought about before.

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